Seminario del Departamento de Física de la Materia Condensada: “How cellular forces and tissue mechanics regulate cell biology”.- Viernes 10 de mayo
El 10 de mayo de 2024 se celebrará una nueva sesión de los Seminarios del Departamento de Física de la Materia Condensada de la Universidad de Zaragoza, con José Manuel García Aznar (Instituto Universitario de Investigación en Ingeniería de Aragón, Universidad de Zaragoza), que ofrecerá la conferencia titulada: “How cellular forces and tissue mechanics regulate cell biology”.
En esta ocasión, la sesión tendrá lugar a las 12:30 horas en una ubicación distinta a la habitual, en el Salón de Actos del Edificio B (Matemáticas) de la Facultad de Ciencias de la Universidad de Zaragoza.
Resumen de la conferencia (en inglés): Biology helps us to understand life, being the cell the smallest basic unit of structure and function that is regulated by various signals from the microenvironment. Mechanical factors are particularly important in this regulation. Thus, mechanobiology focuses on understanding how physical forces regulate changes in the mechanical properties of tissues and cells that subsequently contribute to the physiological functioning of our organism and to that of a disease or pathology. These mechanical forces act not only at the level of an organ but play a relevant role at all spatial scales that make up our tissues, involving the cells and proteins that define them.
This talk will begin with a brief and very basic introduction to mechanobiology. We will then explore the role of mechanobiology at different scales with a more detailed analysis of the mechanopathology of cancer and tumor metastasis. To this end, a dual methodological approach based on computer simulation and microfluidics-based 3D cell culture will be used.
Resumen de su currículo (en inglés): JMGA has devoted his entire research career to the application of engineering technologies to the major problems of our society in the field of Health, especially in Regenerative Medicine, Tissue Engineering, Tumor Metastasis and Immunotherapy.
As a result of this work JMGA presents more than 160 JCR publications with a total of 10262 citations according to Google Scholar. As Principal Investigator JMGA has been leading different European projects of recognized prestige. In fact, he has coordinated up to four ERC (European Research Council) projects: a Starting, two Proof-of-Concepts and an Advanced. He has held different scientific responsibilities at national and international level, including as Vice-President of the European Society of Biomechanics (2008-2012). His level of internationalization is very remarkable, having made research stays in recognized universities (Oxford, Cambridge, Keele University, KU Leuven and NUI Galway).
El ciclo de Seminarios del Departamento de Física de la Materia Condensada cuenta con la colaboración del Instituto de Nanociencia y Materiales de Aragón, INMA, instituto mixto del CSIC y la Universidad de Zaragoza, y la Facultad de Ciencias de la Universidad de Zaragoza.
